NMP-2008-1.3-2 Impact of engineered nanoparticles on health and the environment
Technical content/scope: Continuing and expanding the activities launched with the first FP7 NMP call for proposals, research financing is made available for an understanding of the safety, environmental and human health implications of nanotechnology-based materials and products; this is important worldwide. Reinforced cooperation has been initiated on this matter with several USA federal agencies. It is advantageous to share and harmonize the research effort to increase efficiency and prevent any duplication of effort, also since it addresses pre-competitive questions.
This research will create a reliable and sound foundation for the assessment of the safety of nanotechnology-based products and encourage nanotechnological advances that can address the needs of citizens and contribute to sustainable development objectives. The expected projects should be related to engineered nanoparticles and should address one or more topics in the following areas: (a) potential impact on health; (b) potential impact on the environment.
The expected projects may address one or more of the following issues: hazard characterisation, occupational, human and environmental exposure throughout the life cycle of nanomaterials, toxicology, main endpoints of and health effects of engineered nanoparticles; methodologies for testing; monitoring/detection of engineered nanoparticles in the various environments (excluding the development of equipment); environmental and biological fate, transport, and transformation of nanoparticles in various compartments such as air, water, soil and biological fluids. The interdisciplinary research should contribute to better understanding of toxicokinetics, cellular and molecular mechanisms, behaviour and fate, bio-persistence, biokinetics, to understand fundamentally the exposure, behaviour, mechanisms, consequences and potential effects to various endpoints of nanoparticle-biological entities interactions. In their analysis of the state of the art, the expected proposals should demonstrate clear novelty and not duplicate running or carried aut research, except in duly justified cases.
Funding scheme: Small or medium-scale focused research projects.
Specific features: This topic is well suited for cooperation with research teams from non-EU countries, such as with the USA, Canada, Japan, Korea, Australia and New Zealand, and with ICPC. EU funding is foreseen within the present call only for ICPC, such as Brazil, China, India, Mexico, Russia or South-Africa. Gender issues should be considered, where appropriate.
Expected impact: (i) Better in vitro or in vivo methodologies for the regulatory demands for the safety assessment of nanotechnology products, (ii) better understanding of the impact of the nanoparticles on health, safety and the environment; (iii) future definition of appropriate measures, where needed; (iv) safe and cost-effective minimisation of the exposure of workers; (iv) sustainable and responsible development; (v) support to research and regulation; (vi) implementation of the European Commission’s Action Plan for Nanotechnology; (vii) reinforcement of the international dimension of European research within the 7 th Framework Programme.

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